Browsing by Author "Abourahma, Heba"
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Examining the robustness of a theophylline cocrystal during grinding with additives
Abourahma, Heba; Urban, Jennifer M.; Morozowich, Nicole; Chan, Benny C. (Royal Society of Chemistry, 2012)The robustness of theophylline-p-hydroxybenzoic acid cocrystal (TP·pHBA) while grinding with additives in the solid state was evaluated through a series of solvent-drop grinding experiments with coformers containing various ... -
Modified Birch Reduction for the Introductory Undergraduate Organic Laboratory
Bradley, Lynn M.; Abourahma, Heba; Lareau, Nichole M.; Reesbeck, Megan (American Chemical Society, 2014)The Birch reduction is a reaction commonly taught in the second-year undergraduate organic curriculum that involves the reduction of an aromatic compound to an alicyclic product using sodium metal and liquid ammonia. The ... -
Pyrazinamide cocrystals and the search for polymorphs
Abourahma, Heba; Cocuzza, Devon S.; Melendez, Jesus; Urban, Jennifer M. (Royal Society of Chemistry, 2011)A number of polymorphic cocrystals have been reported in the recent literature, yet there is no clear understanding of the cause or the prevalence of this phenomenon. This study systematically screens for cocrystals of ... -
A tale of two stoichiometrically diverse cocrystals
Abourahma, Heba; Shah, Dhaval D.; Melendez, Jesus; Johnson, Elizabeth J.; Holman, K. Travis (American Chemical Society, 2015)Liquid-assisted grinding of an equimolar amount of pyrazinamide and p-nitrobenzoic acid yields two stoichiometric cocrystals in a 1:1 and 2:1 ratio, respectively. The 2:1 cocrystal was found to be the thermodynamically ...