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    • Doxorubicin physical state in solution and inside liposomes loaded via a pH gradient 

      Li, Xingong; Hirsh, Donald J.; Cabral-Lilly, Donna; Zirkel, Achim; Gruner, Sol M.; Janoff, Andrew S.; Perkins, Walter R. (Elsevier, 12/9/1998)
      We have examined doxorubicin’s (DOX) physical state in solution and inside EPC/cholesterol liposomes that were loaded via a transmembrane pH gradient. Using cryogenic electron microscopy (cryo-EM) we noted that DOX loaded ...