Now showing items 1-2 of 2

    • A Markov Chain Monte Carlo Technique for Identification of Combinations of Allelic Variants Underlying Complex Diseases in Humans 

      Ochs, Michael F.; Favorov, Alexander V.; Andreewski, Timofey V.; Sudomoina, Marina A.; Favorova, Olʹga Olegovna; Parmigiani, Giovanni (Genetics Society of America, 2005)
      In recent years, the number of studies focusing on the genetic basis of common disorders with a complex mode of inheritance, in which multiple genes of small effect are involved, has been steadily increasing. An improved ...
    • Three allele combinations associated with Multiple Sclerosis 

      Ochs, Michael F.; Favorova, Olʹga Olegovna; Favorov, Alexander V.; Boiko, Alexey N.; Andreewski, Timofey V.; Sudomoina, Marina A.; Alekseenkov, Alexey D.; Kulakova, O.G.; Gusev, E.I.; Parmigiani, Giovanni (BioMed Central, 2006)
      Background Multiple sclerosis (MS) is an immune-mediated disease of polygenic etiology. Dissection of its genetic background is a complex problem, because of the combinatorial possibilities of gene-gene interactions. As ...