Browsing by Author "Danilova, Ludmila V."
Now showing items 1-5 of 5
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Correction: novel insight into mutational landscape of head and neck squamous cell carcinoma
Gaykalova, Daria A.; Mambo, Elizabeth; Choudhary, Ashish; Houghton, Jeffery; Buddavarapu, Kalyan; Sanford, Tiffany; Darden, Will; Adai, Alex; Hadd, Andrew; Gary, Latham; Danilova, Ludmila V.; Bishop, Justin A.; Li, Ryan J.; Westra, William H.; Hennessey, Patrick T.; Koch, Wayne M.; Ochs, Michael F.; Califano, Joseph A.; Sun, Wenyue (Public Library of Science, 2020-05-13) -
Hybrid modeling of cell signaling and transcriptional reprogramming and its application in C. elegans development
Ochs, Michael F.; Danilova, Ludmila V.; Favorov, Alexander V.; Fertig, Elana J. (Frontiers Media, 2011)Modeling of signal driven transcriptional reprogramming is critical for understanding of organism development, human disease, and cell biology. Many current modeling techniques discount key features of the biological ... -
Integrative computational analysis of transcriptional and epigenetic alterations implicates DTX1 as a putative tumor suppressor gene in HNSCC
Ochs, Michael F.; Gaykalova, Daria A.; Zizkova, Veronika; Guo, Theresa; Tiscareno, Ilse; Wei, Yingying; Vatapalli, Rajita; Hennessey, Patrick T.; Ahn, Julie; Danilova, Ludmila V.; Khan, Zubair; Bishop, Justin A.; Gutkind, J. Silvio; Koch, Wayne M.; Westra, William H.; Fertig, Elana J.; Califano, Joseph A. (Impact Journals, 2017)Over a half million new cases of Head and Neck Squamous Cell Carcinoma (HNSCC) are diagnosed annually worldwide, however, 5 year overall survival is only 50% for HNSCC patients. Recently, high throughput technologies have ... -
Novel Insight into Mutational Landscape of Head and Neck Squamous Cell Carcinoma
Ochs, Michael F.; Gaykalova, Daria A.; Mambo, Elizabeth; Choudhary, Ashish; Houghton, Jeffery; Buddavarapu, Kalyan; Sanford, Tiffany; Darden, Will; Adai, Alex; Hadd, Andrew; Latham, Gary; Danilova, Ludmila V.; Bishop, Justin A.; Li, Ryan J.; Westra, William H.; Hennessey, Patrick T.; Koch, Wayne M.; Califano, Joseph A.; Sun, Wenyue (Public Library of Science, 2014)Development of head and neck squamous cell carcinoma (HNSCC) is characterized by accumulation of mutations in several oncogenes and tumor suppressor genes. We have formerly described the mutation pattern of HNSCC and ... -
Preferential Activation of the Hedgehog Pathway by Epigenetic Modulations in HPV Negative HNSCC Identified with Meta-Pathway Analysis
Ochs, Michael F.; Fertig, Elana J.; Markovic, Ana; Danilova, Ludmila V.; Gaykalova, Daria A.; Cope, Leslie; Chung, Christine H.; Califano, Joseph A. (Public Library of Science, 2013)Head and neck squamous cell carcinoma (HNSCC) is largely divided into two groups based on their etiology, human papillomavirus (HPV)-positive and –negative. Global DNA methylation changes are known to drive oncogene and ...