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An Expedient in situ Preparation of Symmetrical 1,4-Dibenzylpiperazines from Benzyl Bromides and 2-Bromoethylamine Hydrobromide
A straightforward synthesis of a variety of 1,4-bis-benzylpiperazines from benzyl halides and 2-bromoethylamine hydrobromide is described.
Modified Birch Reduction for the Introductory Undergraduate Organic Laboratory
(American Chemical Society, 2014)
The Birch reduction is a reaction commonly taught in the second-year undergraduate organic curriculum that involves the reduction of an aromatic compound to an alicyclic product using sodium metal and liquid ammonia. The ...