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Fluid dynamics in heart development: effects of hematocrit and trabeculation
(Oxford University Press, 2018-12)
Recent in vivo experiments have illustrated the importance of understanding the haemodynamics of heart morphogenesis. In particular, ventricular trabeculation is governed by a delicate interaction between haemodynamic ...
Uncertainty quantification reveals the physical constraints on pumping by peristaltic hearts
(The Royal Society, 2020-09-09)
Most biological functional systems are complex, and this complexity is a fundamental driver of diversity. Because input parameters interact in complex ways, a holistic understanding of functional systems is key to understanding ...
Diving into a simple anguilliform swimmer’s sensitivity
(Oxford University Press, 2020-09-16)
Computational models of aquatic locomotion range from modest individual simple swimmers in 2D to sophisticated 3D multi-swimmer models that attempt to parse collective behavioral dynamics. Each of these models contain a ...
A semi-automated finite difference mesh creation method for use with immersed boundary software IB2d and IBAMR
(IOP Publishing, 2020-11-27)
Numerous fluid-structure interaction problems in biology have been investigated using the immersed boundary method. The advantage of this method is that complex geometries, e.g., internal or external morphology, can easily ...
Hopscotching jellyfish: combining different duty cycle kinematics can lead to enhanced swimming performance
(IOP Publishing, 2021-10-26)
Jellyfish (Medusozoa) have been deemed the most energy-efficient animals in the world. Their bell morphology and relatively simple nervous systems make them attractive to robotocists. Although, the science community has ...
On the dynamic suction pumping of blood cells in tubular hearts
(Springer, 2017)
Around the third week after gestation in embryonic development, the human heart consists only of a valvless tube, unlike a fully developed adult heart, which is multi-chambered. At this stage in development, the heart ...
IB2d Reloaded: a more powerful Python and MATLAB implementation of the immersed boundary method
(Wiley, 2018-12)
The immersed boundary (IB) method is an elegant way to fully couple the motion of a fluid and deformations of an immersed elastic structure. In that vein, the IB2d software allows for expedited explorations of fluid-structure ...
Fluid-structure interaction for the classroom: interpolation, hearts, and swimming!
(Society for Industrial and Applied Mathematics, 2021)
While students may find spline interpolation quite digestible, based on their familiarity with continuity of a function and its derivatives, some of its inherent value may be missed when students only see it applied to ...
Passive concentration dynamics incorporated into the library IB2d, a two-dimensional implementation of the immersed boundary method
(IOP Publishing, 2022-03-10)
In this paper, we present an open-source software library that can be used to numerically simulate the advection and diffusion of a chemical concentration or heat density in a viscous fluid where a moving, elastic boundary ...