Now showing items 1-10 of 47
Elevated CO2 leads to altered micromechanical properties of the mineralized cuticle in blue and red king crabs
(National Shellfisheries Association, 2014)
Activation of the NOTCH Pathway in Head and Neck Cancer
(American Association for Cancer Research, 2014)
NOTCH1 mutations have been reported to occur in 10% to 15% of head and neck squamous cell carcinomas (HNSCC). To determine the significance of these mutations, we embarked upon a comprehensive study of NOTCH signaling in ...
Gene function analysis
(Humana Press, 2014)
Modified Birch Reduction for the Introductory Undergraduate Organic Laboratory
(American Chemical Society, 2014)
The Birch reduction is a reaction commonly taught in the second-year undergraduate organic curriculum that involves the reduction of an aromatic compound to an alicyclic product using sodium metal and liquid ammonia. The ...
Two Clinical Phenotypes in Polycythemia Vera
(Massachusetts Medical Society, 2014)
Background Polycythemia vera is the ultimate phenotypic consequence of the V617F mutation in Janus kinase 2 (encoded by JAK2), but the extent to which this mutation influences the behavior of the involved CD34+ hematopoietic ...
RDA: Resource Description & Access—Reports from the Field
Novel Insight into Mutational Landscape of Head and Neck Squamous Cell Carcinoma
(Public Library of Science, 2014)
Development of head and neck squamous cell carcinoma (HNSCC) is characterized by accumulation of mutations in several oncogenes and tumor suppressor genes. We have formerly described the mutation pattern of HNSCC and ...
Evaluating the Effects of Ocean Acidification on the Mechanical Properties of King Crabs and Tanner Crabs
Ocean Acidification (OA) is a decrease in the ocean’s pH caused by increasing levels of CO2 in the atmosphere. Dissolution of CO2 in ocean water results in decreased CaCO3 saturation states, which affect the ability of ...
Determination of Optimum Surface Profile for Bond of Fiber Reinforced Polymer (FRP) to Concrete
The American Society of Civil Engineers has rated the infrastructure of the United States at a startling D+ and estimates that one in every nine bridges is structurally deficient. They also predict that by 2020, 3.6 million ...