Now showing items 1-10 of 457
Building context with tumor growth modeling projects in differential equations
(Taylor & Francis, 2015)
The use of modeling projects serves to integrate, reinforce, and extend student knowledge. Here we present two projects related to tumor growth appropriate for a first course in differential equations. They illustrate the ...
Matrix Factorization Methods Applied in Microarray Data Analysis
Numerous methods have been applied to microarray data to group genes into clusters that show similar expression patterns. These methods assign each gene to a single group, which does not reflect the widely held view among ...
Synthesis, Characterization, and Reactivity Studies of (Cyclohexenyl)nickel(II) Complexes
(American Chemical Society, 7/13/2010)
Hybrid modeling of cell signaling and transcriptional reprogramming and its application in C. elegans development
(Frontiers Media, 2011)
Modeling of signal driven transcriptional reprogramming is critical for understanding of organism development, human disease, and cell biology. Many current modeling techniques discount key features of the biological ...
Global Reactivation of Epigenetically Silenced Genes in Prostate Cancer
(American Association for Cancer Research, 2010)
Transcriptional silencing associated with aberrant promoter hypermethylation is a common mechanism of inactivation of tumor suppressor genes in cancer cells. To globally profile the genes silenced by hypermethylation in ...
CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network
(Impact Journals, 2016)
Patients with oncogene driven tumors are treated with targeted therapeutics including EGFR inhibitors. Genomic data from The Cancer Genome Atlas (TCGA) demonstrates molecular alterations to EGFR, MAPK, and PI3K pathways ...
Sneak peek: Raptors search for prey using stochastic head turns
(Central Ornithology Publication Office, 2017)
The strategies by which foraging predators decide when to redirect their gaze influence both prey detection rates and the prey's ability to detect and avoid predators. We applied statistical analyses that have been used ...
Microenvironmental Niches and Sanctuaries: A Route to Acquired Resistance
A tumor vasculature that is functionally abnormal results in irregular gradients of metabolites and drugs within the tumor tissue. Recently, significant efforts have been committed to experimentally examine how cellular ...
Guide to the solo horn repertoire
(Indiana University Press, 2016)
A Primer on Building Library Mobile Website
(Chinese American Librarian Association, 2011)
This paper aims to help libraries develop the mobile web. It focuses on practical techniques and skills, showing in detail how to build a mobile web from scratch, and how to perform testing. It contains code examples from ...