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    Stabilizing Effect of a Bacterial Lipid Membrane on Type IV Pilin Subunits 

    Brier, Troy; Baker, Joseph L. (2015)
    Type IV pili are thin, long, strong, flexible filaments that are found in gram-positive and gram-negative bacteria. They stretch out from pores in the membrane of the bacteria. These filaments are very important for many ...

    Probing the stability of the C-terminal domain of type IV pilins under external force 

    Goncalves, Rebecca B.; Baker, Joseph L. (2016)
    Type IV pili (T4P) are long bio-filaments, assembled from many copies of a protein called pilin, which emanate from the surface of bacterial cells (Fig. 1). They are used to adhere to other surfaces and other cells. T4P ...
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    Steered Molecular Dynamic Simulations of the Neisseria Meningitidis Type IV Pilus Reveal Structural Changes under Force 

    Baker, Joseph L.; Marin, Kevin G. (2019)
    Our group is using computer simulations to investigate the strength of bacterial filaments called type IV pili. Type IV pili extend from bacterial cells and are used in a wide variety of functions, including adhesion, ...
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    Analysis of Insulin Monomer in the Deep Eutectic Solvent Choline Geranate Using Molecular Dynamics 

    Baker, Joseph L.; Piscitelli, Jonathan; Lindberg, Gerrick E. (2019)
    Our group is using computer models of molecular systems to better understand the impact of deep eutectic solvents on the protein insulin. Specifically, we are studying how the deep eutectic solvent choline geranate stabilizes ...

    Exploring the biomechanics of type IV pilus filaments under force using coarse grained molecular dynamics 

    Bogin, Bryan A.; Goncalves, Rebecca B.; Baker, Joseph L. (2017)
    Type IV Pili (T4P) are long biopolymers made up of thousands of copies of a protein called pilin. T4P are found on a large variety of micro-organisms including Gram-positive and Gram-negative bacteria [1]. It has been ...
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    Investigating the Role of the Melted Region in Type IV Pili Filaments Using Steered Molecular Dynamics Simulation 

    Baker, Joseph L.; Lovenduski, Christopher; Bogin, Bryan A.; Fairfield, Maria N.; Jones, Stephen J.; Biais, Nicolas (2019)
    Our group is using computer simulations to investigate the strength of bacterial filaments called type IV pili. Type IV pili extend from bacterial cells and are used in a wide variety of functions, including adhesion, ...

    Examining the impact of removing cross-linking disulfide bonds on the stability of an Ena Pilus filament under applied tension force 

    Baker, Joseph L.; Chaudhry, Ayesha (2023)
    Spore-forming bacteria are an issue because they can ruin and spoil food and can make people sick. These bacterial spores can stick to many surfaces, withstand high heat, and are hard to kill even with disinfectants. ...

    The impact of n-terminal strand removal on the structure and functionality of the s-ena pili on bacterial endospores 

    Baker, Joseph L.; Bondalapati, Spandana (2023)
    Bacillus cereus sensu lato is a group of Gram-positive human and animal pathogens, which (as a survival mechanism) are able to become endospores that can withstand starvation, antimicrobials, wet heat, radiation, and strong ...

    Determining the strength of the interaction energies between subunits of Ena Pili filaments through steered molecular dynamics 

    Baker, Joseph L.; Wielowski, Karolina (2023)
    Bacillus cereus sensu lato is a gram-positive bacteria with the ability to form endospores. Endospore appendages isolated from B. cereus NVH 0075-95, nicknamed the ‘S-Ena Pili” exhibit unique structural characteristics, ...

    Identifying components of a stable docking site for histatin 5 on e.coli 

    Baker, Joseph L.; Grewal, Iknoor (2023)
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    Baker, Joseph L. (20)
    Bogin, Bryan A. (2)Goncalves, Rebecca B. (2)Lindberg, Gerrick E. (2)Alseika, Zachary L. (1)Andrews, Aleena (1)Biais, Nicolas (1)Bondalapati, Spandana (1)Brier, Troy (1)Castro, Rebeca S. (1)... View MoreDate Issued2019 (5)2023 (4)2015 (3)2022 (3)2016 (2)2017 (2)2018 (1)Has File(s)Yes (15)No (5)

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