Search
Now showing items 1-9 of 9
Set2 and Prp28 function in forward and reverse coupling of transcription and splicing
(2015)
There is a series of steps that must take place for proper gene expression to occur. Two of those steps, transcription and splicing, have been shown to be coordinated. Although not much is known about the mechanism by which ...
Elucidating the Role of Histone H4 Acetylation in RNA Splicing in Saccharomyces Cerevisiae
(2019)
In order for appropriate gene expression to be carried out in eukaryotes, there must be strict regulation between steps in gene expression. Two key steps are transcription, in which an RNA copy of the DNA gene is created, ...
Identifying proteins that coordinate RNA synthesis with splicing: effects of a esa1-254 point mutation on splicing in yeast
(2021)
The ability for the eukaryotic cell to maintain homeostasis depends significantly on the cell’s adaptability to changes in surrounding environments. In order to maintain an internal balance, protein synthesis is highly ...
Coupling between key steps in gene expression: a role for the NuA4 histone acetyltransferase and the variant histone Htz1 in co-transcriptional RNA processing
(2021)
Gene expression is a tightly regulated process that involves properly synthesizing an RNA transcript from DNA, and splicing it correctly to prepare it for proper translation into a protein. We focused on two key steps: ...
Prion formation [PSI+] and benefits in S. cerevisiae
(2021)
Prion formation in S. cerevisiae is still a relatively new field of yeast molecular biology. In opposition to prions in humans, these protein misfoldings are thought to be beneficial to cell survival in response to ...
A novel connection between [PSI+] prion formation and RNA splicing in S. cerevisiae
(2022)
Relatively new studies on prions in Saccharomyces cerevisiae show that some protein prion conformations may be beneficial to cell survival in response to environmental stress. Sup35, a translation termination release factor, ...
Investigating the coordination of transcription and RNA splicing via chromatin modification
(2016)
All cells need to be able to respond to changes in their environment. The process that cells use to respond to environmental stimuli is gene expression, in which certain genes are expressed to generate the proteins required ...