Now showing items 1-3 of 3

    • Fluid dynamics in heart development: effects of hematocrit and trabeculation 

      Battista, Nicholas; Lane, Andrea; Liu, Jiandong; Miller, Laura (Oxford University Press, 2018-12)
      Recent in vivo experiments have illustrated the importance of understanding the haemodynamics of heart morphogenesis. In particular, ventricular trabeculation is governed by a delicate interaction between haemodynamic ...
    • On the dynamic suction pumping of blood cells in tubular hearts 

      Battista, Nicholas; Lane, Andrea N.; Miller, Laura A. (Springer, 2017)
      Around the third week after gestation in embryonic development, the human heart consists only of a valvless tube, unlike a fully developed adult heart, which is multi-chambered. At this stage in development, the heart ...
    • Vortex dynamics in trabeculated embryonic ventricles 

      Battista, Nicholas; Douglas, Dylan R.; Lane, Andrea; Samsa, Leigh Ann; Liu, Jiandong; Miller, Laura (MDPI, 2019-01-22)
      Proper heart morphogenesis requires a delicate balance between hemodynamic forces, myocardial activity, morphogen gradients, and epigenetic signaling, all of which are coupled with genetic regulatory networks. Recently ...