Browsing Mathematics & Statistics Department by Subject "Genomics"

Now showing items 1-2 of 2

    • Enter the matrix: factorization uncovers knowledge from omics 

      Stein-O’Brien, Genevieve L.; Arora, Raman; Culhane, Aedin C.; Favorov, Alexander V.; Garmire, Lana X.; Greene, Casey S.; Goff, Loyal A.; Li, Yifeng; Ngom, Aloune; Ochs, Michael F.; Xu, Yanxun; Fertig, Elana J. (Cell Press, 2018-10)
      Omics data contain signals from the molecular, physical, and kinetic inter- and intracellular interactions that control biological systems. Matrix factorization (MF) techniques can reveal low-dimensional structure from ...

    • Outlier Analysis and Top Scoring Pair for Integrated Data Analysis and Biomarker Discovery 

      Ochs, Michael F.; Farrar, Jason E.; Considine, Michael; Wei, Yingying; Meshinchi, Soheil; Arceci, Robert J. (Institute of Electrical and Electronics Engineers, 2013)
      Pathway deregulation has been identified as a key driver of carcinogenesis, with proteins in signaling pathways serving as primary targets for drug development. Deregulation can be driven by a number of molecular events, ...