Photochemistry of 2-pyridones with para-substituted benzenes
Rossiter, Lauren M.
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In pharmaceuticals, there is a large use of complex heterocyclic scaffolds that require long syntheses. Specifically, drugs containing pyridones are becoming increasingly more common, especially with containing 2-pyridones. The aim of this research is to use photochemistry to create organic heterocycles with a shorter synthesis. Photochemistry can be used to synthesize complex molecules in a single step using UV irradiation. A shorter synthesis saves both time and money. In this research, the aim is to synthesize 2-pyridones tethered to para-substituted benzenes and then use these molecules as photosubstrates, expose them to UV light at ~290 nm and make complex heterocycles. We aim to analyze the photoproducts, determine their molecular structure, and observe any patterns when the benzene is para substituted.
Department of Chemistry
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